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HelpTest Code G6PD1 Glucose 6-Phosphate Dehydrogenase Enzyme Activity, Blood
Specimen Required
Collection Container/Tube:
Preferred: Yellow top (ACD solution B)
Acceptable: Lavender top (EDTA) or yellow top (ACD solution A)
Specimen Volume: 6 mL
Collection Instructions: Send specimen in original tube. Do not aliquot.
Secondary ID
607460Useful For
Evaluation of individuals with episodic or chronic Coombs-negative nonspherocytic hemolytic anemia
Rapid testing to assess glucose 6-phosphate dehydrogenase (G6PD) enzyme capacity prior to rasburicase or other therapies that may cause hemolysis or methemoglobinemia in G6PD deficient patients
May aid in the creation of a comprehensive patient profile and can ensure appropriate patient monitoring for developing anemia
Testing Algorithm
The following are available:
-Glucose-6-Phosphate Dehydrogenase (G6PD) Deficiency Diagnostic Algorithm
-Glucose-6-Phosphate Dehydrogenase (G6PD) Genotyping Interpretive Algorithm
-Newborn Screen Follow-up for Glucose-6-Phosphate Dehydrogenase (G6PD) Deficiency
-Newborn Screening Act Sheet Glucose-6-Phosphate Dehydrogenase Deficiency
Special Instructions
- Newborn Screening Act Sheet Glucose-6-Phosphate Dehydrogenase Deficiency
- Newborn Screen Follow-up for Glucose-6-Phosphate Dehydrogenase (G6PD) Deficiency
- Glucose-6-Phosphate Dehydrogenase (G6PD) Genotyping Interpretive Algorithm
- Glucose-6-Phosphate Dehydrogenase (G6PD) Deficiency Diagnostic Algorithm
Method Name
Kinetic Spectrophotometry
Reporting Name
G6PD Enzyme Activity, BSpecimen Type
Whole Blood ACD-BSpecimen Minimum Volume
1 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Whole Blood ACD-B | Refrigerated | 20 days |
Reject Due To
| Gross hemolysis | Reject |
Reference Values
≥12 months of age: 8.0-11.9 U/g Hb
Reference values have not been established for patients who are less than 12 months of age.
Specimen Retention Time
7 daysPerforming Laboratory
Mayo Clinic Laboratories in Rochester
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
82955
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| G6PD1 | G6PD Enzyme Activity, B | 32546-4 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| G6PCL | G6PD Enzyme Activity, B | 32546-4 |
Day(s) Performed
Monday through Friday
Report Available
1 to 4 daysForms
If not ordering electronically, complete, print, and send a Benign Hematology Test Request (T755) with the specimen.