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HelpActivated Protein C Resist,P
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3.2% Sodium Citrate
Specimen Requirements
Preferred:
Container/Tube: Blue Top (Citrate Tube)
Minimum Volume: 1 mL Blood
Collection Instructions: Patient must not be receiving heparin. Spin immediately.
Specimen Stability
Analyze within 1 Hour: Use Primary Tube
Analyze within 4 Hours:
Spin immediately. Remove the top 2/3 plasma within 1 hour and spin again. Remove the top 2/3 of the plasma from
this sample for testing.
Analyze > 4 Hours: Remove the top 2/3 plasma within 1 hour and spin again. Remove the top 2/3 of this sample and freeze at -70 degrees
Reference Range
Ratios ≤1.5 suggest Factor V Leiden
Ratios >1.5 <2.1 may suggest low levels of protein C
Ratios >1.5 are considered normal
Methodology
Fixed absorbance: Clotting Assay
CPT
85307
Test Alias
APC-Resistance
Lab Handling
Remove the top 2/3 plasma and transfer to plastic tube. Spin again. Remove 1 mL from the top and put in a plastic tube. Freeze immediately.
Day(s) Performed
Tuesday and Thursday
Report Available
1-5 days