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Mayo Clinic Laboratories

Pathology Tissue Request

Icon & Photo

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Specimen Requirements

Tissue Pathology

For Routine Gross and Microscopic Examination or for Routine Gross Examination Only

  • Tissue, Fixed in 10% Formalin unless microbiology, cytogenetic studies or flow cytometry are requested then must be submitted fresh (No Preservative).
  • Intraoperative gross and microscopic evaluation of specimen. Pathologist will report back to procedure room with preliminary result.

  • Frozen Section/Intraoperative gross exam
    • Tissue, Fresh (No Preservative).
    • Pathologist will report results to OR room
  • Lymph Node Protocol
    • Tissue, Fresh (No Preservative).
    • Evaluation of lymph node (or mass) tissue to diagnose lymphoma v. other. Tissue will be triaged for additional testing (Flow Cytometry, Cytogenetics, Microbiology) as needed by pathologist.
  • Product of Conception, Chromosomes
    • Tissue, Fresh
    • Fill out disposal order form
    • Please obtain maternal blood for Parental Sample Prep for Prenatal Microarray Testing, Blood, (Mayo code PPAP)
Muscle/ Nerve Biopsy

Mon-Thur 0800-1600 only

Fresh on saline soaked gauze

Send to Histology immediately

Skin Biopsy for Immunofluorescence

Assessment of connective tissue disorders, bullous diseases, and certain types of vasculitis.

  • one biopsy in formalin for immunofluorescence
  • one biopsy in Michel's solution

 

Specimen Stability

 

Ambient: If formalin has been added

Refrigerate: If no Formalin has been addded

Frozen: Not applicable

Laboratory Retention: 3 weeks after final report

Turn Around Time

Monday-Friday 0800-1600 

3-7 business days

Reference Range

Interpretive report provided by pathologist