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HelpNMR LipoProfile® With Lipids (Without Graph)
Additional Codes
884247, NMR LipoProfile+Lipids
Use
NMR LDL-P is a management tool used in appropriate high-risk patients (type 2 diabetes mellitus, metabolic syndrome, CVD risk equivalent, statin-treated patients) to adjudicate response to treatment and guide adjustment in therapy. It is used in conjunction with other lipid measurements and clinical evaluation to aid in the management of lipoprotein disorders associated with cardiovascular disease.
Custom Additional Information
The NMR LipoProfile® test is a blood test that directly measures the amount of LDL circulating in the body. “LDL” is low-density lipoprotein and has long been recognized as a major causal factor in the development of heart disease. Although the relationship of increased LDL particle number and plaque buildup in the artery wall has been known since the 1950s, a diagnostic test did not exist to measure LDL particle number (LDL-P). Historically, LDL cholesterol, or LDL-C, has been used to estimate LDL levels to assess a patient’s LDL-related cardiovascular risk and judge an individual’s response to LDL-lowering therapy. The NMR LipoProfile® test reports results for LDL-P, a more reliable measure of LDL that directly counts the number of LDL particles a patient has using NMR technology.
Note: If triglyceride level is >800 mg/dL, LDL cholesterol will not be calculated.
This test was developed and its performance characteristics determined by Labcorp. It has not been cleared or approved by the Food and Drug Administration.
Icon & Photos
Red Top Tube (no gel)
Specimen Requirements
Preferred:
Container/Tube: Red Top Tube (no gel)
Minimum Volume: 1 mL Serum
Collection Instructions: Gently invert tube eight to 10 times to mix contents and allow specimen to clot for 30 minutes upright at room temperature prior to centrifugation (plasma tubes should not clot). Centrifuge specimen within two hours of collection at 1600 to 1800 xg for 10 to 15 minutes to separate serum/plasma from the red cells. If the sample cannot be centrifuged immediately, the sample should be refrigerated (at 2ºC to 8ºC) and centrifuged within 24 hours of collection.
Also Acceptable:
Container/Tube: Lavender Top EDTA (no gel), Green Top Heparin (no gel), NMR LipoTube (black-and-yellow-top gel-barrier tube)
Specimen Stability
Rerfigerate: 6 days
Methodology
Nuclear magnetic resonance (NMR)
Note: The NMR method for Triglycerides, unlike the routine chemical method, is not affected by endogenous glycerol, which might be found in very rare clinical conditions such as Hyperglycerolemia (glycerol kinase deficiency-GKD), an X-linked genetic disorder. Large quantitative differences in the chemical and NMR method results may be attributable to high blood glycerol.
CPT
80061
83704
Test Alias
NMR LipoProfile+Lipids
NMR LipoProfile®
NMR LDL-P
LDL Particle Size
Report Available
2 - 3 days