Test Code TAPNS Tapentadol and Metabolite, Serum
Specimen Required
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Collection Container/Tube: Red top (Serum gel/SST are not acceptable)
Submission Container/Tube: Plastic vial
Specimen Volume: 1.0 mL Serum
Collection Instructions: Within 2 hours of collection, centrifuge and aliquot serum into a plastic vial.
Secondary ID
624021Useful For
Monitoring medication compliance in patients who are prescribed tapentadol
Method Name
Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)
Reporting Name
Tapentadol and Metabolite, SSpecimen Type
Serum RedSpecimen Minimum Volume
Serum: 0.5 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum Red | Refrigerated (preferred) | 14 days |
| Frozen | 28 days | |
| Ambient | 14 days |
Reject Due To
| Gross hemolysis | OK |
| Gross lipemia | OK |
| Gross icterus | OK |
Reference Values
Tapentadol:
Therapeutic: 5-300 ng/mL
N-desmethyltapentadol:
No therapeutic range established
Cutoff concentrations by liquid chromatography tandem mass spectrometry:
Tapentadol: 0.5 ng/mL
N-desmethyltapentadol: 0.5 ng/mL
Day(s) Performed
Tuesday
Report Available
3 to 7 daysSpecimen Retention Time
14 daysPerforming Laboratory
Mayo Clinic Laboratories in Rochester
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
G0480
80372 (if appropriate for select payers)
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| TAPNS | Tapentadol and Metabolite, S | In Process |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 624021 | Tapentadol | 59354-1 |
| 624022 | N-desmethyltapentadol | In Process |